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World’s First Advanced TAVR Procedure at UPMC Harrisburg

An 82-year-old woman from Elliottsburg, Pennsylvania, has successfully undergone a new type of transcatheter aortic valve replacement (TAVR) at UPMC Harrisburg, marking the first worldwide use of the newest-generation FDA-approved Evolut™ FX+ TAVR system. The procedure was performed by Hemal Gada, M.D., president of UPMC Heart and Vascular Institute in Central Pa., who is the first interventional cardiologist globally to utilize this system.

The Evolut FX+ TAVR system, designed for treating symptomatic severe aortic stenosis, features a modified diamond-shaped frame that provides larger coronary access windows, facilitating easier management of future cardiovascular procedures. This system builds on the legacy Evolut TAVR platform while offering enhanced valve performance and reduced pacemaker rates.

Severe aortic stenosis, a condition where the aortic valve becomes stiff and thickened, forces the heart to work harder, significantly affecting the patient’s quality of life and potentially leading to heart failure if untreated.

UPMC Heart and Vascular Institute has a longstanding history of pioneering cardiovascular treatments since 1956, including being the first in the region to perform open heart surgery and various minimally invasive cardiac procedures. The institute recently received the highest three-star rating from The Society of Thoracic Surgeons in multiple categories, placing it among the top cardiac surgery programs in North America. For further details, visit


Patricia M Campbell 1932-2024

Pat graduated from Fannett Township High School in 1950 and received her BA in Education from, known then as, Shippensburg State Teachers College. .

James Patrick McNally III 1947-2024

James was known for his dedication and excellence in his professional career, where he made lasting contributions and built strong relationships with his colleagues.

Brenda Jackson Liu 1945-2024

Upon retirement, Brenda worked as a part-time nurse at the Migrant Health in Gettysburg. During this time she traveled to migrant camps all over Pennsylvania.

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